Filtration<br />Solutions

Filtration
Solutions

Our proprietary continuous, small scale rotary filtration and washing system purifies diluted to concentrated suspensions containing active pharmaceutical ingredients (APIs) or API intermediates.

Our filtration solution

Continuous Rotary Filter: Our novel proprietary continuous filter purifies the crystallization slurry, removing unwanted impurities from the Active Pharmaceutical Ingredient (API) or intermediate product. This process can take less than a minute. The slurry is deposited on a rotating porous plate, where the mother liquor is filtered out through a vacuum system. The thin (1 to 6 mm) wet-cake is effectively and efficiently purged of impurities through the application of multiple wash stations, after which it is transported to the next unit. An in-line cleaning mechanism restores the filter plate, while the purified wet-cake is analyzed with in-line PATs for real-time purity and concentration. The system has the ability to segregate filtrate streams, enhancing solvent recovery.

Related Paper

All published articles that relate to this specific technology and solution.

A Continuous Rotary Filtration for the Separation and Purification of an API
A Continuous Rotary Filtration for the Separation and Purification of an API
Design and Commercialization of an End-to-End Continuous Pharmaceutical Production Process: A Pilot Plant Case Study
Design and Commercialization of an End-to-End Continuous Pharmaceutical Production Process: A Pilot Plant Case Study
E-factor analysis of a pilot plant for end-to-end integrated continuous manufacturing (ICM) of pharmaceuticals
E-factor analysis of a pilot plant for end-to-end integrated continuous manufacturing (ICM) of pharmaceuticals
Design of a Continuous Solvent Recovery System for End-to-End Integrated Continuous Manufacturing (ICM) of Pharmaceuticals
Design of a Continuous Solvent Recovery System for End-to-End Integrated Continuous Manufacturing (ICM) of Pharmaceuticals
An automated modular assembly line for drugs in a miniaturized plant
An automated modular assembly line for drugs in a miniaturized plant