ICM enables seamless end-to-end continuous manufacturing processes that incorporate API formation steps with final drug product formulation.

End-to-End Solutions

By eliminating all the stops-and-starts that make current manufacturing processes time- and cost-inefficient, we are able to attain all the benefits associated with continuous manufacturing. Important underlying principles include continuous flow, an end-to-end strategy, a systems approach, and an integrated control system. The following case study, based on pilot studies performed at CONTINUUS’s facility, demonstrate how ICM can provide advantages over an already well-established and optimized batch process

Watch below for the video of our pilot plant in action and the results of our case study

High Potency Drugs and other Special Cases

The integrated nature of ICM processes eliminates points of human exposure – process material and intermediates remain in situ, and are transported across the different unit operations through automated and closed processes. This is particularly beneficial for manufacturers of high potency compounds, where containment challenges are significant. Furthermore, the small in-process volumes characteristic of ICM systems further improve operator safety.

Processes with unstable or explosive intermediates can also benefit significantly from ICM implementation. This is because with ICM processes, these intermediates are generated on demand, and are immediately consumed (i.e., they are not isolated and then manually transported to the next step), reducing the build-up of such dangerous materials.

Other Advantages

Due to its unique features, such as its use of novel continuous technologies, ICM can provide advantages across the entire supply chain (see figure below).


CONTINUUS have engineered end-to-end ICM solutions, which integrates both the upstream production of API and the downstream formulation steps into a single seamless continuous process.


CONTINUUS will offer clients significant advantages during commercial manufacturing. For companies that do not require in-house production