Our Crystallization solutions
Mixed-Suspension, Mixed-Product Removal (MSMPR) Crystallization: The most simple and general system to perform crystallizations, a multi-stage MSMPR crystallizer is typically utilized to convert batch crystallizations to continuous ones.
Heterogeneous Crystallization: API in different solutions can be crystallized on crystalline or polymeric excipients to eliminate downstream processes such as granulation.
Integrated Nucleator and Tubular Crystallizer: A supersaturated solution is run into a nucleator device containing a specific seed initiating the nucleation process. Particles are then transferred into a tubular (plug flow) crystallizer where growth occurs.
Related Paper
All published articles that relate to this specific technology and solution.
Process Development for Continuous Manufacturing of Baloxavir Marboxil. Part 2: Step 2 Synthesis
Process Development toward the Continuous Manufacturing of Baloxavir Marboxil
Targeting Particle Size Specification in Pharmaceutical Crystallization: A Review on Recent Process Design and Development Strategies and Particle Size Measurements
Heterogeneous Crystallization as a Process Intensification Technology in an ICM Process for Pharmaceuticals
Design and Commercialization of an End-to-End Continuous Pharmaceutical Production Process: A Pilot Plant Case Study